Life Cycle Of The Malaria Parasite
A mosquito causes an infection by a bite (1). The sporozoites enter the bloodstream, and migrate to the liver. They infect liver cells, where they multiply into merozoites, rupture the liver cells, and return to the bloodstream (2). The merozoites infect red blood cells, where they develop into ring forms, trophozoites and schizonts that in turn produce further merozoites (3). Sexual forms (gametocytes) are also produced (4), which, if taken up by a mosquito with the blood(5), mature in the mosquito gut to gametes. The male and female gametes fuse (6) and form an ookinete—a fertilized, motile zygote able to cross the midgut wall as Oocyst. Oocyst develop new sporozoites that migrate to the insect's salivary glands (7), ready to infect a new vertebrate host.
Related Vectors
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